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The Effects of Sb2O3 on Human Health

In their effort to evaluate selected chemicals from the 2021, 2022, 2023, and 2024 threshold limit value (TLV) – time-weighted average (TWA) document published by the American Conference of Governmental Industrial Hygienists (ACGIH), the WorkSafeBC Exposure Limit Review Committee (ELRC) tasked the Evidence-Based Practice Group (EBPG) to investigate the health effects, regarding to the development of lung cancer and/or other non-cancer lung diseases, of occupational exposure to antimony trioxide (Sb2O3) with a significant lowering of the TLV-TWA. In their 2021 publication, the ACGIH lowered the TLV-TWA of (Sb2O3) to 0.02 mg/m3 from a previous level of 0.5 mg/m3 in 1978/1979. In their documentation1, the ACGIH stated that this lowering in the TLV-TWA of (Sb2O3) was expected to protect against non-malignant and malignant lung effects.

Publication Date: Feb 2025 File type: PDF (315 KB) Asset type: Research